The number of males to infect at outset determines
how many males are given a random Wolbachia infection at the
start of the simulation. Randomly-generated infections have two genes
and five plasmids, with each being a random toxin or antitoxin (only
the toxins are active in males).
The number of females to infect at outset determines
how many females are given a random Wolbachia infection at
the start of the simulation (only antitoxins are active in females).
The toxin/antitoxin length determines how long the
binary strings for these simulated chemicals are. For example, if this
is set to the default of 4, a toxin might look like
this: 0110. If this toxin were produced in a male, it
would be cancelled out by an antitoxin of the same string
(0110) in a female.
The CI rate determines how potent toxins are — that
is, how likely a non-neutralized toxin is to kill a given offspring.
Survival odds are therefore equal to
(1 - CI_RATE)TOXIN_COUNT.
The CI rescue rate determines how likely a
perfectly-matched antitoxin is to neutralize its toxin — if this is
1, and the female parent has one antitoxin perfectly
matching every toxin produced by her male mate, all their offspring
will survive.
The duration determines the maximum length of the
simulation in days. At the end of this duration (or at the point
Wolbachia is eliminated entirely or infects everyone,
whichever comes first), a JSON file containing data from the
simulation will automatically be downloaded. Mosquitoes take 14 days
to reach maturity.